FEIT Research Project Database

Integration in biofabrication: biomaterial strategies for seamless tissue repair

Project Leader: Andrea O'Connor
Collaborators: Claudia Di Bella (Surgery)
Primary Contact: Andrea O'Connor (a.oconnor@unimelb.edu.au)
Keywords: biofabrication; biomaterials; bioprinting; polymeric materials; tissue engineering
Disciplines: Biomedical Engineering

Biofabrication and tissue engineering have enormous potential to address clinical needs and develop substitutes to restore, maintain, or improve tissue and organ functions. Ideally, new healthy tissue of the targeted type grows and replaces the gradually degrading biomaterials used to create the desired environment, leaving a functional tissue that is well integrated into the body. However, poor integration of these engineered tissue constructs with native tissue in the body often limits clinical outcomes.

This project focuses on biomaterial strategies to overcome this challenge by improving the interaction between engineered tissues and native tissues. It has applications in engineering of a wide range of tissue types including articular cartilage where the forces on joints make seamless integration particularly important and challenging.

This project involves collaboration between the Department of Biomedical Engineering at the University of Melbourne and clinicians and scientists at BioFab3D and ACMD.

Further information: https://biomedical.eng.unimelb.edu.au/tissue-engineering https://biomedical.eng.unimelb.edu.au/ https://www.acmd.org.au/