FEIT Research Project Database

Study of brain organoids to understand dementia

Project Leader: Vini Gautam
Primary Contact: Vini Gautam (vini.gautam@unimelb.edu.au)
Keywords: brain; electrical stimulation; nanotechnology; neuroengineering; neuroimaging and neuroinformatics
Disciplines: Biomedical Engineering

In this project, we will develop novel strategies for diagnosis and treatment of Alzheimer’s Disease (AD) using brain organoids.

We will develop brain organoids (mini-brains) from stem cells taken from AD patients as well as individuals unaffected by the disease. Then we will develop and use state-of-the-art measurement and stimulation techniques to evaluate the function of these organoids and better understand the disease. Artificial-intelligence-based techniques will be used along the project to supplement the experiments. This project will be carried out in collaboration with experts in relevant areas.

The PhD candidate under this project will have the unique opportunity to:

  1. Solve a challenging high-impact problem
  2. Travel and collaborate with researchers across Australia
  3. Learn hand-on skills in a wide range of fields simultaneously – neuroscience, medicine, stem cells, physics and engineering – opening doors to various job prospects after completion of their degree

Interested applicants with a relevant background should contact Dr Vini Gautam at vini.gautam@unimelb.edu.au for further details and discussion. Please include your CV and a brief description of your research interests and/or aspirations.