FEIT Research Project Database

Stentrode stimulation: feasibility of an endovascular stimulation for monitoring excitability of brain networks

Project Leader: Sam John
Staff: David Grayden
Primary Contact: Sam John (sam.john@unimelb.edu.au)
Keywords: neural engineering; neuroengineering
Disciplines: Biomedical Engineering
Research Centre: Neuroengineering Research Laboratory

Epilepsy affects over 65 million people worldwide and approximately 30% of sufferers do not benefit from drugs. Traditional methods of treating drug-resistant epilepsy involve placing electrodes into the brain, requiring risky open-brain surgery. Unlike existing technology, we are developing a Stentrode Neuro-Stimulator (SNS) for the treatment of drug-resistant epilepsy and other neurological conditions without the need for open-brain surgery. The Stentrode is a stent-electrode, using electrodes mounted on a stent to stimulate the brain through a blood vessel without the need for open-brain surgery. This project will be performed in close collaboration with Synchron Australia, a pre-revenue Australian start-up company. The SNS comprises a prototype Stentrode, wireless telemetry and the control software to stimulate the brain for the diagnosis and monitoring of epilepsy and forecasting and alleviating seizures.

Unlike existing, highly invasive technologies, the SNS avoids the need for open-brain surgery by stimulating and recording brain signals from within a blood vessel. The minimally invasive procedure that may be performed in the outpatient setting. We are the first group in the world to develop this technology giving us the advantage of being first to market.

Further information: https://biomedical.eng.unimelb.edu.au/john-neurobionics/research