MSE Research Project Database

Advanced 3D bioprinting: cell micromanipulation across hierarchical length scales


Project Leader: David Collins
Primary Contact: Dr. David Collins (david.collins@unimelb.edu.au)
Keywords: biomaterials; bioprinting; biotechnology; micro-fluidics; tissue engineering
Disciplines: Biomedical Engineering
Domains:

Bioprinting has the promise to replace human tissues that are damaged by injury or disease. Bioprinting involves extruding a cell-laden hydrogel in a specific configuration, with cells subsequently proliferating in this hydrogel matrix. Despite the promise of this technology, there is currently no way to replicate many tissue functions because there is no reliable way to replicate the single-cell configurations found in real-life organs. This project aims to use microscale forces (acoustic, electrical, hydrodynamic, etc.) to manipulate at the single-cell level to create functional human tissues with a view toward creating therapies and research tools. 

This interdisciplinary project lies at the intersection of Biomedical Engineering, Mechanical Engineering, Microfluidics and Cell Biology. Prospective students with experience or special interest in:

  • cell culture
  • 3D printing
  • microfabrication
  • biomedical technology
  • computer simulation
  • microscale physics  

are encouraged to apply.

Successful applicants will be expected to conduct research at a high level and publish in internationally recognized journals. Students will be given wide latitude to determine specific methods and research directions that serve the project goal.

Your lead supervisor will be Dr. David Collins, a new Lecturer in the Biomedical Engineering Department. You will have one co-supervisor from elsewhere in the department.

Further information: www.davidjohncollins.com