FEIT Research Project Database

System identification in biology

Project Leader: Jonathan Manton
Collaborators: Professor Tony Burgess
Primary Contact: Jonathan Manton (jmanton@unimelb.edu.au)
Keywords: signal processing; signals and systems; system identification; systems biology
Disciplines: Electrical & Electronic Engineering
Research Centre: Nonlinear Signal Processing Lab

System identification is a core signal processing discipline which studies how best to estimate the parameters of a model from observations. Biological systems, such as cell signalling pathways, have characteristics quite different from classically engineered systems. Furthermore, there are generally more restrictions on the type of measurements that can be made on biological systems compared with engineered systems. It is therefore timely to refine and extend the theory of system identification to increase its effectiveness in systems biology.