MSE Research Project Database

Random search strategies: modelling and analysis of T cell movement


Project Leader: Jonathan Manton
Collaborators: Professor William Heath
Primary Contact: Jonathan Manton (jmanton@unimelb.edu.au)
Keywords: random search strategies; signal processing; signals and systems; systems biology
Disciplines: Electrical & Electronic Engineering
Domains:
Research Centre: Nonlinear Signal Processing Lab

Prevention of illnesses such as malaria rely on T cells in the liver finding all pathogens within the incubation period. It is therefore natural to ask how many T cells are required to patrol the whole liver within a fixed period of time. Other questions include understanding how the search time is influenced by the topology of the search space and the random process driving the T cells. This project will study these and other questions, all related to random search strategies.