MSE Research Project Database

Can stem cell derived cardiac cells be used for patient-specific drug screening?

Project Leader: Vijayaraghavan Rajagopal
Collaborators: David Thorburn (MCRI)
Primary Contact: Vijay Rajagopal (
Keywords: biocellular systems engineering; biomechanics; heart; systems biology
Disciplines: Biomedical Engineering,Mechanical Engineering
Domains: Convergence of engineering and IT with the life sciences
Research Centre: Systems Biology Laboratory

The aim of this project is to work with our collaborators to develop experimental and computational models of stem cell-derived cardiac cells under normal and disease conditions to investigate whether stem cell derived myocytes can be used as replacements to animal models for patient-specific drug screening. 


A cardiac cell cross-section depicting myofibrils and mitochondria in adult myocytes under normal conditions