MSE Research Project Database

Microfluidics


Project Leader: Ivan Marusic
Staff: Jimmy Philip
Student: Farzan Akbaridoust
Primary Contact: Ivan Marusic (imarusic@unimelb.edu.au)
Keywords: micro-fluidics
Disciplines: Mechanical Engineering
Domains: Convergence of engineering and IT with the life sciences

Mechanical properties of red blood cells change when people suffer from certain diseases. As such, characterisation of the mechanical properties of these cells is important.  Recent advances in microfluidic systems have enabled researchers to manipulate single cells and measure the deformability of the cells in fluid flows. Here at the Department of Mechanical Engineering the Fluid Mechanics Group have developed the capability of confining single micron-sized objects in extensional flows.

The aim of this project is to develop a robust method for quantifying the mechanical properties of biological micron-sized materials including blood and cancerous cells and microorganisms. The project involves fabrication of microfluidic devices, micron-resolution particle image velocimetry (micro-PIV) measurements, and real-time flow control in microchannels.

Overlaid images of the confinement of a cyanobacterial filament in the cross-slot microchannel using active control syst
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Micro-PIV and real-time control experimental setup
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