MSE Research Project Database

Modelling of neural plasticity for enhanced performance of brain-machine interfaces

Project Leader: Anthony Burkitt
Staff: Catherine Davey, David Grayden
Primary Contact: Anthony Burkitt (
Keywords: biomedical engineering; computational neuroscience; medical bionics; neural models; neuroengineering
Disciplines: Biomedical Engineering
Domains: Convergence of engineering and IT with the life sciences

Plasticity of the brain is one of the great scientific challenges of neuroscience. The aim of this project is to model the synaptic changes that occur with reward-modulated spike-timing-dependent plasticity and apply the model to developing plasticity targeted brain-machine interfaces. The significance of this approach is that such plasticity targeted techniques provide the prospect of taking advantage of the underlying neural plasticity to optimise the form of the neural recording and electrical stimulation. The outcomes will be to greatly improve the performance of brain-machine interface in terms of measures such as the number and sensitivity of channels, as well as robustness and reliability.